Study Sheds Light On Origins Of Diabetes
An international study unprecedented in both scale and scope has provided some important answers to the mysteries of how diabetes developsnot least of which is the answer to a century-old debate about whether genetic differences are shared and common, or rare and individual.
Led by researchers from the United States and England, more than 300 scientists from 22 countries used DNA from 120,000 individuals to pinpoint genes and their variants.
The collaboration brought together two research projects: GoT2D and T2D-DENES. The research teams completed whole-genome sequencing of more than 2,600 people and exome sequencing of 12,940, as well as genome- or exome-wide array genotyping of 111,548 people. Unlike most previous studies, which involved only people of European ancestry, this study included people with ancestral origins in Europe, South and East Asia, the Americas, and Africa.
The conclusions seem clear, agreed Mark McCarthy, Group Head of the Wellcome Trust Centre for Human Genetics. He noted, he evidence is increasingly stacking up in favor of the view that most of the genetic risk of T2D can be attributed to common alleles that are widely shared within, and between, human populations.
Talk With Your Doctor First
If you think you may have depression, you should first consult with a mental health professional, like a psychiatrist, or reach out to your primary care provider. A doctor can evaluate your symptoms and discuss treatment options, ranging from supplements that may help manage your mood to lifestyle changes or medication.
In some cases, supplements can interfere with other medications, or even worsen symptoms in some people, so you should always consult with a doctor, and never attempt to treat your depression entirely on your own.
In most cases, alternative treatment options like herbs and supplements are best suited for those with mild depressive symptoms, characterized by short periods of low moods. While they may be enough to help someone with mild depression manage their mood, these options may not be effective for those with more severe depressive symptoms.
“The challenge is figuring out what works for you and when, if necessary, to switch to the more traditional treatments because the symptoms are interfering with your life,” says Kevin Gilliland, Psy. D, a licensed clinical psychologist and executive director of Innovation360, an outpatient counseling service that serves people with mental health and substance abuse issues.
While supplements are not regulated by the FDA, third-party laboratories, like Consumer Lab, do test supplements for potency and accuracy, so you can check to see if a supplement has been tested before you buy one.
Supplements For Bipolar Depression
Lithium Orotate Can Curb Mania and Help Bipolar Depression
Treatment for bipolar disorder is a little more complex than just depression. Manic depression has two dangerous sides on the one end you swing into depression and on the other end you swing into mania. 5-HTP and other supplements can help with being depressed, but sometimes can produce too much mania.
The main thing with bipolar is eliminating substances like sugar, coffee, and stimulants that can promote a manic episode and taking some of the supplements above to help with depression.
Research shows that high amounts of fish oil is clinically significant in helping people overcome bipolar. If you suffer from bipolar symptoms and arent eating any fish or taking fish oil, start now!
Lecithin has been found to stabilize moods and has been effective in getting rid of a manic episode. Some people find that it stabilizes mood while others have found that it can depress them.
Lithium orotate has been found to help many people manage their bipolar disorder. There is some conflicting evidence that taking it long term might not be the best option, but hundreds and hundreds of people still take it everyday. If youve struggled for years with bipolar, are taking fish oil and vitamins/minerals, have your diet under control and have checked to see if you are sensitive to sugar, Id suggest trying lithium orotate among other natural remedies for bipolar and seeing how it affects you.
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Depression Stress And Anxiety
Adjusting to a chronic, debilitating illness sometimes leads to other problems, including depression, stress, and anxiety. Many patients with ME/CFS develop depression during their illness. When present, depression or anxiety should be treated. Although treating depression or anxiety can be helpful, it is not a cure for ME/CFS.
Some people with ME/CFS might benefit from antidepressants and anti-anxiety medications. However, doctors should use caution in prescribing these medications. Some drugs used to treat depression have other effects that might worsen other ME/CFS symptoms and cause side effects. When healthcare providers are concerned about patients psychological condition, they may recommend seeing a mental health professional.
Some people with ME/CFS might benefit from trying techniques like deep breathing and muscle relaxation, massage, and movement therapies . These can reduce stress and anxiety, and promote a sense of well-being.
The Top 7 Best Herbs For Depression
Depression is something that afflicts almost everyone at some point in their lives as either a mild or severe emotional issue. Because its so common, its no surprise that there are so many cultures and medical traditions that have used herbs to treat depression throughout time! While there are many highly effective chemical antidepressants available by prescription today, some people prefer to go a more natural route with treating their depression. If youre looking for an affordable, safe, and effective way to treat mild to moderate depression symptoms, then a herbal treatment protocol may be right for you.
Make sure to speak to a licensed healthcare professional before taking any of these herbs. While most of these herbs are very safe when taken in small quantities to treat depression, its important to seek advice. This ensures that there arent any contraindications between the herbs and medications that you may currently be taking.
If you have a particular medical condition or are in a unique medical situation , you also need to check with your healthcare professional to make sure that these herbs and supplements are safe for you.
In another trial, St. Johns Wort was administered to patients along with folic acid. The combination functioned by modulating serotonin receptors and assisting in the breakdown of serotonin and noradrenalin, successfully treating depressive symptoms.
Lavender
BONUS SUPPLEMENTS: Acids and SAM-e
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Vitamin B: A Serotonin Cofactor
Serotonin is the main brain chemical responsible for feeling happy, relaxed, and confident.
It also plays an important role in sleep, sex drive, and digestive health.
The most prevalent theory of depression is that its caused by a lack of serotonin.
This is why the most commonly prescribed antidepressants are selective serotonin reuptake inhibitors which work by increasing serotonin levels in the brain.
Normally, serotonin is created in the brain and body from tryptophan, an amino acid commonly found in meat, poultry, fish, and dairy products.
Tryptophan provides the basic building blocks used to synthesize serotonin, but certain cofactors vitamin B6, folic acid, vitamin C, iron , magnesium , calcium , and zinc must be present for this reaction to take place.
You can see that vitamin B6 is used twice in this two-step conversion process, which helps explain the correlation between low blood levels of vitamin B6 and depression.
Vitamin B6 is also needed to make dopamine, another neurotransmitter associated with depression.
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Theres a growing body of evidence that chronic brain inflammation may be a root cause of depression.
Vitamin B6 Supplement Dosages
The RDA for vitamin B6 is 1.3 mg daily for most adults.
Pregnant women need more as do seniors .
So What Really Is The Best Natural Treatment For Mental Health Issues
No single strategy will work for everyone. The treatment for your mental health condition needs to be just as individual as you are.
In the experience of most practitioners , you will have the best chances to fully recover from depression and anxiety if you follow the 7-step strategy and process outlined here
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Exhale Wellness Overall Best Supplements For Depression Editors Pick
Exhale Wellness is an excellent brand for anyone who suffers from depression. The company makes high-quality CBD products, including gummies and oils.
Customers dont have to pay anything until they are delighted with their purchase. If you do not need or dislike your purchase within 30 days, you will have your money back without any questions asked. This policy makes it easier for those who want to try out different products without worrying about wasting money if they dont like them. Or if they dont see results after taking them.
Exhale Wellness uses CO2 extraction to produce its products. This method is one of the most effective and safest ways to make CBD oil. This process allows the company to extract the compounds within hemp instead of just some of them, as other methods do. The process also removes most residual solvents from the final product. Therefore, you dont have to worry about harmful chemicals being left behind.
Customers enjoy vegan gummies that do not contain gelatin or animal products. These gummies are also gluten-free and made with natural flavors, which makes them great for people with food allergies or sensitivities. However, other flavors are available if you want something other than vegan options.
Highlights
Pros
Supplements For Depression And Sleep
Many supplements that also help with sleep have already been mentioned above. If you want a more in depth look at which supplements help sleep, check out one of the most popular articles on this site My Secret Combination of Supplements That Knock You Out.
Holy basil can help with irritability and depression if stress is what is keeping you awake. L-Tryptophan works wonders if you are a Xanax addict. Valerian root is a good short term option. But check out the article above for a more in depth look on what works and what doesnt.
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When Combined With Evidence
Depression is a mood disorder, and its one of the most common mental health conditions that people experience. Different terms used to refer to depression include major depressive disorder and clinical depression. While many people require clinical treatment and perhaps pharmaceutical medications to treat the symptoms of depression, there are also certain vitamins that can be helpful for depression. Along with vitamins for depression, there are also natural supplements for anxiety and depression that can be helpful for treating symptoms of these co-occurring disorders.
Symptoms of depression include significant changes in feelings, thoughts and behaviors, including loss of interest in activities that a person previously enjoyed and an ongoing, persistent feeling of sadness. Depending on the severity of the depression, a person may experience different physical and emotional problems related to the disorder.
Natural Supplements For Depression
What is Depression and Anxiety?
Many who suffer with anxiety disorder may also suffer from depression, and the same goes for those who suffer from depression, may be affected by anxiety. The good news is the treatment for these disorders typically involve similar interventions. With depression, one may feel sad, unmotivated, hopeless or disinterested in daily activities, whereas anxiety can occur before or after depression, or can be experienced all on its own. Of course, its common for everyone to feel this way every once in awhile, but when this feeling is ongoing, lasting weeks and interfering with daily life, is when it can lead to a diagnosis.
What are the Symptoms of Depression?
Symptoms of Depression to look out for include:
What are the Symptoms of Anxiety?
Common symptoms of Anxiety include:
Genetics and Depression
Is there a gene that makes one more susceptible to depression, or is a nutritional deficiency at the root cause? Research has linked certain nutrient deficiencies with specific genes, making some people predisposed to having lower concentrations of vitamins, such as vitamin D, B12 and B6 in the body.
Also Check: Do You Have To Get Diagnosed With Depression
Fish Oil Supplements For Depression
Carlson Labs Fish Oil is Well Worth the Price
This list wouldnt be complete if I didnt mention fish oil. It is one of the supplements I take every single day no matter what. Why? Your brain is 60% fat. By getting enough Omega-3s in your diet and through supplementation, your brain will function much better. Fish oil is better than flax, as some people cant convert flax properly into DHA and EPA.
- Carlson Liquid Fish Oil This stuff is amazing and I miss it everyday as I am traveling. It is fresh, high quality fish oil. You can either take a spoonful every morning or you can even drizzle a little bit on salads.
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How Much Is Too Much
Your body filters out excess water-soluble vitamins , so its difficult to overconsume these. However, fat-soluble vitamins like vitamin D are stored in fat tissues and can be dangerous in excess. While there is no upper limit established for omega-3s, high doses may interact with some anticoagulant medications. You can ensure you arent exceeding the upper limits of any vitamin or mineral by running your supplements by a healthcare provider.
When it comes to other types of supplements like herbs and other compounds, safe amounts will vary and may depend on your health status and other supplements and medications you are taking. Its always best to discuss the dosing of any supplements with a healthcare provider first.
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The Top Herbal Supplements For Depression
Herbs have been used traditionally to treat depression in every culture.
Apparently, depression is not just a modern problem.
Heres a look at some of the best herbal supplements those with a long history of safe use that have also been scientifically proven to be effective.
Caution:If you currently take a prescription antidepressant, talk to your doctor before making any changes to your medication.
More About Chronic Fatigue Syndrome
It is a complex disorder that is characterized by persistent fatigue associated with other symptoms that aren`t relieved by rest yet not associated with any medical disorder.
It hinders you from doing your daily activities normally.
CFS is a medical condition that is accompanied with unexplained fatigue
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How Do You Buy The Best Natural Supplement For Depression
Do you get stressed out thinking about shopping for a great natural supplement for depression? Do doubts keep creeping into your mind?
We understand, because weve already gone through the whole process of researching natural supplement for depression, which is why we have assembled a comprehensive list of the greatest natural supplement for depression available in the current market. Weve also come up with a list of questions that you probably have yourself.
John Harvards has done the best we can with our thoughts and recommendations, but its still crucial that you do thorough research on your own for natural supplement for depression that you consider buying. Your questions might include the following:
- Is it worth buying an natural supplement for depression?
- What benefits are there with buying an natural supplement for depression?
- What factors deserve consideration when shopping for an effective natural supplement for depression?
- Why is it crucial to invest in any natural supplement for depression, much less the best one?
- Which natural supplement for depression are good in the current market?
- Where can you find information like this about natural supplement for depression?
Were convinced that you likely have far more questions than just these regarding natural supplement for depression, and the only real way to satisfy your need for knowledge is to get information from as many reputable online sources as you possibly can.
How We Select Supplements
Our team works hard to be transparent about why we recommend certain supplements you can read more about our dietary supplement methodology here.
We support supplements that are evidence-based and rooted in science. We value certain product attributes that we find to be associated with the highest-quality products. We prioritize products that are third-party tested and certified by one of three independent, third-party certifiers: USP, NSF, or ConsumerLab.
It’s important to note that the FDA does not review dietary supplements for safety and effectiveness before they go to market. Our team of experts has created a detailed, science-backed methodology to choose the supplements we recommend.
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Which Supplements Are Best For Depression
Numerous studies have evaluated the role of supplements in treating depression. Nonetheless, not all studies are of equal quality and its important to consider findings from rigorous studies published in high quality journals. A Harvard affiliated analysis published in the American Journal of Psychiatry completed a comprehensive evaluation of existing studies , offering a condensed and reliable way to review what works. They analyzed existing study results across 16 different depression-related supplements to determine which ones had sufficient evidence to suggest they help reduce symptoms of depression when taken with antidepressant medication.
Here are the depression supplements they found to be successful:
Fish oil is high in omega-3 fatty acids, which are key to certain brain functions and may help reduce inflammation associated with depression. There are two types of omega-3s in fish oil: EPA and DHA. Researchers found that EPA is the one that helps the most when it comes to depression.
Certain people have a genetic makeup that actually impairs their use of folic acid in cellular processes, which may be associated with depression. Supplementing with L-methylfolate can help bridge this gap and keep the cellular processes moving. In fact, there is already an FDA-approved form of L-methylfolate that doctors prescribe to individuals who dont initially respond to antidepressant treatment.