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Many people with depression have worked hard to treat their disease. You may attend therapy and take your antidepressants, only to find that the numbers on the scale are moving up and your clothes are not fitting like they used to. While you may feel better emotionally and mentally, you might also feel discouraged by your physical appearance or health.
Some of this may be due to the connection between antidepressants and weight gain. It is not a side effect of every medication used to treat depression, and some are more associated with weight loss.
However, any side effectweight gain includeddepends entirely on how your body reacts to the medication. It is possible that you will notice no change in weight or that you will swing in the opposite direction of what’s typical, no matter which medication you take. For some people, the fluctuation in weight is only temporary.
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What To Do If You Feel Antidepressants Are Affecting Your Weight
If you are one of the estimated 25% of patients who gain weight when taking antidepressants, you may well be contemplating throwing your pills down the drain! But before you make this drastic move, its important to share your concerns with your physician.
As with anything, you must consider the benefits versus the side effects of the medication. If you and your doctor believe the positives outweigh the negatives, you can control your weight by changing other aspects of your lifestyle. For example:
Ask your doctor to refer you to a nutritionist who will help to evaluate your ideal weight and advise you on what sort of dietary changes you can make to reach it.
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If you have gained weight while taking antidepressants, try to incorporate exercise into your daily schedule. You can do aerobics in your house, go for a jog, ride a bike, or walk. If you have not exercised in a while, consult your doctor beforehand and ease yourself in.
Use alternative medication
Although many antidepressants affect weight, some have more severe effects than others.
You can ask your doctor if it is advisable to switch your medication or adjust the dosage. Most importantly, remember to weigh the pros and cons of all your options before making a final decision.
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Bupropion is a norepinephrine-dopamine reuptake inhibitor which acts to inhibit the reuptake or absorption of chemicals or neurotransmitters in the brain. These neurotransmitters include dopamine, serotonin, and norepinephrine. Depression is thought to occur due to an imbalance in the amounts of neurotransmitters released from neurons on brain cells. Bupropion therefore works to allow more dopamine, serotonin and norepinephrine to be available and improve your mood.
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Recommended Reading: How Does Depression Make You Lose Weight
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According to the Mayo Clinic, clinical depression can be treated by psychotherapy as well as medication 1. Antidepressants affect the release and reuptake of some common neurotransmitters that send messages between neurons 2. Some of these include dopamine, serotonin, and norepinephrine. Common antidepressant groups include selective serotonin re-uptake inhibitors , monoamine oxidase inhibitors , and tricyclic antidepressants 2.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
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You should never stop taking Lexapro abruptly. If you do, you can experience withdrawal symptoms, including irritability, dizziness, nightmares, headaches, nausea, or a tingling sensation on your skin. Your healthcare provider will slowly decrease your dose of Lexapro to help avoid these symptoms as you wean off the medication. Speak with your doctor before making any changes to your medications.
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Before 2012, there were few weight loss medications approved by the U.S. Food and Drug Administration . The top medications at that time were phentermine and orlistat.
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Antidepressants are medications used to manage the symptoms of depression, anxiety, dysthymia, and seasonal affective disorder, among many other conditions. The medications work by balancing brain neurotransmitters, the catalysts of changes in mood and behavior.
There are many types of antidepressants, and they differ depending on how they work within the brain. Some are preferred over others for treating certain conditions, but one thing they all have in common is their potential side effects. This is the reason many patients take time to try out different medications before they find the one that is best suited to them.
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Since then, as now, no one really knew how to deal with this type of weight gain we decided to try an approach that had worked with typical obese clients. We knew from our research and previous clinical experience that increasing serotonin synthesis increased satiety. The SSRIs that theoretically should have activated this serotoninergic function were doing just the opposite, i.e. causing the patients to feel a chronic need to eat.
All carbohydrates with the exception of fructose will lead to an increase in serotonin synthesis if the carbohydrate is consumed without protein. The process involves the uptake into the brain of the amino acid tryptophan, the precursor to serotonin. Insulin release after carbohydrate digestion removes from the circulation other amino acids that compete with tryptophan for brain uptake. Tryptophan enters the brain easily and is quickly converted into serotonin. Protein consumption, even if eaten along with carbohydrates, floods the circulation with these competitor amino acids, and tryptophan, the scarcest amino acid in protein, does not get into the brain.
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Fluoxetine is not a medication that is ideal for everyone with clinical depression, OCD, or other mood disorders. You should not take it if you are aware of an allergy or hypersensitivity to fluoxetine or if you also take pimozide . Before you take fluoxetine, your doctor will need to go through your medical history and check that you do not have any other health issues which would affect how well this medicine will work. Let you doctor know if you have any of the following:
- Seizures or epilepsy, being treated with electroconvulsive therapy
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Fluoxetine is one of the most studied antidepressants in pregnancy. Nevertheless, there is no established evidence that it is absolutely safe to take during pregnancy and while breast-feeding. Talk to your doctor about the benefits and risks of taking your antidepressant while pregnant.
Fluoxetine can potentially interact with numerous medications, increasing or decreasing its concentration in the blood or how well it works. Such fluoxetine interactions can also cause preventable side-effects. It is therefore important that your doctor knows what other medications you are currently taking before prescribing fluoxetine. You also need to make sure you notify your doctor if you start or stop taking over-the-counter medications or off-the-counter supplements while on fluoxetine.
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