Monoamine Oxidase Inhibitors Side Effects
Monoamine oxidase inhibitors are a class of antidepressant associated with postural hypotension , high blood pressure, fainting, abnormal heart rhythm, dizziness, headache, drowsiness, insomnia, anxiety, constipation, nausea, diarrhea, sexual dysfunction, weight gain or weight loss, and edema. Seizures, rash, blurred vision, and hepatitis are infrequently associated with MAOIs.
What Can I Do To Take Antidepressants Safely
Antidepressants are generally safe when you use them correctly:
- Tell your provider about everything you take. That includes medicines, herbs, supplements, and over-the-counter medicines you take, such as pain relievers and decongestants. Be honest about recreational drugs and alcohol, too.
- Try to get all your medicines from the same pharmacy. That way the pharmacist can warn you and your provider if you take medicines that may cause problems when used together.
- Follow all instructions about how to take your medicine.
- Talk with your provider if side effects bother you.
- Never stop taking antidepressants without your provider’s help. Stopping too fast may make depression come back. You could even make your condition worse. To stop antidepressants safely, you need to give your body time to get used to being without the medicine. Your provider can tell you the safest way to go off an antidepressant.
NIH: National Institute of Mental Health
What Are Side Effects Of Antidepressants
Antidepressants that belong to the same class of antidepressant produce similar side effects. Antidepressants may cause withdrawal symptoms if abruptly discontinued. Withdrawal symptoms include nausea, vomiting, dizziness, headache, irritability, sleep disturbance, nightmares, psychosis, and seizures. All antidepressants have a warning about use in children and adolescents. Antidepressants increased the risk of suicidal thinking, and suicidal behavior in short-term studies in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of antidepressant in a child or adolescent must balance this risk of suicide with the clinical need for the drug. Patients who are started on therapy should be closely observed for clinical worsening, suicidal thoughts or unusual changes in behavior.
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Selective Serotonin Noradrenaline Reuptake Inhibitors
Both SSNRI and SSRI medications affect serotonin levels, but SSNRI drugs also impact the level of norepinephrine, another neurotransmitter that may affect mood. This type of medication is helpful for those who have extreme fatigue associated with depression, or who have had side effects or poor response to SSRI drugs.
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Alternative Treatments For Depression And Anxiety
Some people get better with psychological therapy alone. Others find it best to use a combination of antidepressants and psychological therapy.
There are many different psychological therapies. The most common is cognitive behavioural therapy. This therapy aims to identify and change your negative thoughts.
Other types of therapy aim to get you to accept your thoughts and environment in a non-judgemental way, or help you change patterns of behaviour that are not helpful.
Talk to your doctor about options for treatment. You might be eligible for a mental health care plan, which reduces the cost of treatment.
There are other things that help your anxiety and depression.
- Exercise can help improve your mood and self-esteem as well as reducing the risk of weight gain .
- If you smoke, quitting reduces depression, anxiety and stress, and improves mood.
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Selective Serotonin Reuptake Inhibitors
SSRIs are the most widely prescribed type of antidepressants. They’re usually preferred over other antidepressants, as they cause fewer side effects. An overdose is also less likely to be serious.
Fluoxetine is probably the best known SSRI . Other SSRIs include citalopram , escitalopram , paroxetine and sertraline .
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How Long Do Depression Pills Take To Work
The time it takes for many antidepressants to start working is between 1 and 3 weeks. It can take a long time before they reach their full potential. Depression symptoms such as lack of interest in things that used to be enjoyable and feelings of hopelessness and sadness will eventually improve with treatment.
How Long Does It Take Antidepressants To Work
Taking an antidepressant is not like taking other medications where the effects are obvious minutes or hours after consumption. You have to take the medication consistently, as prescribed, for at least four weeks before you may start to feel the benefits. In some cases, it could take additional weeks for the effects to fully take hold.2
You have to work with your prescriber to determine an appropriate dose for your symptoms and unique biology. Some people find that dose quickly, while others might have to start at a lower dosage and build a higher dosage slowly and over time.
Always work with your prescriber to communicate your needs, goals, and symptoms. Never stop taking your medication without first consulting with your treatment team.2
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What Are The Side Effects Of Antidepressants
Like all medications, antidepressants can have side effects. Over half of all people who take antidepressants have side effects. They usually occur during the first few weeks of treatment and are less common later on.
Some of these side effects are believed to be a direct consequence of the medication’s effect on the brain and are relatively similar among various drugs within the same group. Examples include a dry mouth, headaches, dizziness, restlessness and sexual problems. These kinds of problems are often perceived to be side effects of the medications. But some of them may be caused by the itself.
Whether or not someone has side effects, which side effects they have, and how frequent they are will depend on the drug, the dose used, and whether they have just started taking it or have been taking it for some time. And everyone reacts slightly differently to drugs too. The risk of side effects increases if you are also taking other medication. One of the drugs may make the side effects of the other worse. These kinds of drug interactions are common in older people and people with chronic illnesses who are taking several different kinds of medication.
For this reason, it’s important to thoroughly discuss the pros and cons of the various medications with your doctor.
Some side effects are more common with particular drugs:
How Do Antidepressants Work For Depression
Depression, or major depressive disorder, is a common and serious medical illness characterized by persistently depressed mood and loss of interest in activities significant enough to cause substantial impairment in day-to-day life. Because of their symptoms, people with depression may struggle to get out of bed in the mornings, and simple tasks like brushing their hair or changing their clothes can be draining.
Antidepressants reduce symptoms of depression by balancing chemicals in the brain called neurotransmitters, which affect mood and emotions, particularly dopamine and serotonin. These depression medications can improve your mood, concentration, sleep, and increase your appetite.
For people with depression, antidepressants can help jump-start their moods and give them the boost they need to manage their symptoms and complete their daily tasks and responsibilities. Depression medication can also encourage these individuals to do the things they enjoy again, and make better choices for themselves, contributing to an overall improved sense of being.
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How Is Depression Treated
Depression is treatable with high rates of success. Treatments may include:
- Antidepressants, such as Selective Serotonin Reuptake Inhibitors , Serotonin Norepinephrine Reuptake Inhibitors , tricyclic antidepressants , monoamine oxidase inhibitors .
Responses to antidepressants vary, and most antidepressants take 4 to 6 weeks for full effect. About 50% of patients respond to the first treatment, whereas others may have to try a few different types of antidepressants before they find the best one for them.
There are several things you can do to help with your symptoms as well, such as:
- Setting realistic and daily goals
- Developing strategies to work through crises situations
- Developing coping and problem-solving skills
- Learning how to develop positive relationships
- Replacing negative thoughts with positive ones.
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How To Take Antidepressants
Antidepressants are usually taken every day. It can take 1 or even 2 months to see the full results. You may need to try different kinds or amounts to find the antidepressant that works best for you.
Your doctor will let you know how long to take your antidepressant. If this is the first time you have been treated for depression, you will probably continue to take this medicine for at least 6 months after you begin to feel better. If this is the second time youve been depressed, you might keep taking the medicine for at least a year. Depression that comes back a third time may require you to continue taking an antidepressant for a longer time.
You can get unwanted side effects if you stop taking your antidepressant suddenly. If you want to stop taking your medicine, talk to your doctor first. He or she can try to help you avoid these side effects.
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What If An Antidepressant Doesnt Work
If you donât notice any change in your mood after a few weeks, talk with your doctor. If the first antidepressant you take doesnât work, itâs likely that another one will. About 60% of people who take antidepressants feel better with the first medicine they take, but others need to try more than one before noticing a change.
A study funded by the National Institute of Mental Health in 2008 found that about 50% of patients who did not feel better after using one medication noticed an improvement when they took a new one or added a second medication to the first treatment. You and your doctor can work together to find the medication thatâs right for you.
âI had to try a couple of different kinds of medications to find the right one for me,â Brennan tells WebMD. âOne medication worked for a little while, and then I started to feel depressed again. So my doctor switched me to another medication, and that one is working great. Itâs just a matter of sticking with it and letting your doctor know how youâre feeling.â
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Antidepressant Effects And Abuse
Antidepressants are among the most prescribed medications in the United States. Many doctors prescribe SSRI and SNRI Antidepressants as a safer alternative to Benzodiazepines. Doctors consider Antidepressants safer because the drugs have less potential for abuse. Despite this, some people abuse Antidepressant medications.
A small but growing literature on the misuse and abuse of Antidepressants consists largely of case reports. The most commonly reported motivation for abuse is to achieve a psychostimulant-like effect.
– Columbia University Department of Psychiatry, Abuse and Misuse of Antidepressants, 2014
Antidepressants dont have the euphoric effects other drugs have. In other words, Antidepressants cant get the user high. That doesnt stop some people from trying, though. Some people think since Antidepressants improve mood that high doses must induce euphoria, but that is not how the drugs work.
Antidepressants work over time, accumulating in the brain. They dont produce immediate effects. It can take over a month before an Antidepressant starts working.
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